Thyroid cancer (cancer of the thyroid gland) comes in four variations: papillary, follicular, medullary and anaplastic. Papillary and medullary are slow-growing and sometimes return, but respond well to treatment in patients under middle age.
Medullary also reacts well to treatment, if it has not already spread. Anaplastic grows rapidly and reacts badly to therapy. The extent of these types of cancer is not uniform throughout the world, but is roughly: 78% for papillary; 17% for follicular; 4% for medullary and 1% for anaplastic.
Usually, the first symptom of difficulty is the growth of a nodule or nodules in the neck in close proximity to the thyroid gland. However, only 5% of these are malignant. Occasionally an early warning sign is discomfort or even pain; sometimes, the lymph nodes swell, the voice alters or there is hypo- or hyper- thyroidism.
Diagnosis usually takes place after a nodule is discovered during a (general) physical examination. The patient is then sent to an endocrinologist or a thyroidologist, who will arrange an ultrasound test or a biopsy. Using a fine needle enough cells can be taken to do an accurate test on the precise state of the thyroid and whether the nodules are cancerous.
Papillary thyroid cancer more often occurs in women and often in the 30-40 year old age group and is frequently characterized by bulging eyes. If the growth is less than 1cm in size a partial thyroidectomy or hemithyroidectomy would almost certainly be recommended.
Above 1cm and a full thyroidectomy is preferred. Some surgeons would rather a full thyroidectomy anyway because the cancer cannot come back then.
Follicular thyroid cancer is more common in women over 50 years of age. Therapy is most frequently full thyroidectomy as the threat of recurrence of this aggressive kind is too great for partial surgery.
Medullary thyroid cancer (MTC) begins in the cells that produce the hormone calcitonin. Increased degrees of calcitonin in the blood are a reasonable indication of MTC, although these elevated degrees of calcitonin are almost certainly not injurious in themselves.
Changes in the DNA concerned in cell growth and development are responsible for nearly all cases of hereditary or familial medullary thyroid carcinoma. Hereditary medullary thyroid cancer is inherited as a 50/50 likelihood from every affected parent. DNA analysis makes it possible to identify children who carry the mutant gene.
Surgical removal of the thyroid in children who carry the mutant gene is effective if the entire thyroid gland is removed at an early age, before there is a spread of the tumor. Hereditary MTC accounts for about 25% of all cases of MTC. The other 75% of cases are called sporadic MTC and normally happen in older patients.
Frequently the disease is well advanced in these cases as there has been no screening as in hereditary MTC. The first sign is frequently diarhoea. The likelihood of surviving MTC seem to be related to the rate at which the patient?s post operative calcitonin levels double.
Anaplastic thyroid cancer is highly aggressive and likelihood of survival are almost zero. It is resistant to all known cancer medications and invades nearby tissue rapidly.
Medullary also reacts well to treatment, if it has not already spread. Anaplastic grows rapidly and reacts badly to therapy. The extent of these types of cancer is not uniform throughout the world, but is roughly: 78% for papillary; 17% for follicular; 4% for medullary and 1% for anaplastic.
Usually, the first symptom of difficulty is the growth of a nodule or nodules in the neck in close proximity to the thyroid gland. However, only 5% of these are malignant. Occasionally an early warning sign is discomfort or even pain; sometimes, the lymph nodes swell, the voice alters or there is hypo- or hyper- thyroidism.
Diagnosis usually takes place after a nodule is discovered during a (general) physical examination. The patient is then sent to an endocrinologist or a thyroidologist, who will arrange an ultrasound test or a biopsy. Using a fine needle enough cells can be taken to do an accurate test on the precise state of the thyroid and whether the nodules are cancerous.
Papillary thyroid cancer more often occurs in women and often in the 30-40 year old age group and is frequently characterized by bulging eyes. If the growth is less than 1cm in size a partial thyroidectomy or hemithyroidectomy would almost certainly be recommended.
Above 1cm and a full thyroidectomy is preferred. Some surgeons would rather a full thyroidectomy anyway because the cancer cannot come back then.
Follicular thyroid cancer is more common in women over 50 years of age. Therapy is most frequently full thyroidectomy as the threat of recurrence of this aggressive kind is too great for partial surgery.
Medullary thyroid cancer (MTC) begins in the cells that produce the hormone calcitonin. Increased degrees of calcitonin in the blood are a reasonable indication of MTC, although these elevated degrees of calcitonin are almost certainly not injurious in themselves.
Changes in the DNA concerned in cell growth and development are responsible for nearly all cases of hereditary or familial medullary thyroid carcinoma. Hereditary medullary thyroid cancer is inherited as a 50/50 likelihood from every affected parent. DNA analysis makes it possible to identify children who carry the mutant gene.
Surgical removal of the thyroid in children who carry the mutant gene is effective if the entire thyroid gland is removed at an early age, before there is a spread of the tumor. Hereditary MTC accounts for about 25% of all cases of MTC. The other 75% of cases are called sporadic MTC and normally happen in older patients.
Frequently the disease is well advanced in these cases as there has been no screening as in hereditary MTC. The first sign is frequently diarhoea. The likelihood of surviving MTC seem to be related to the rate at which the patient?s post operative calcitonin levels double.
Anaplastic thyroid cancer is highly aggressive and likelihood of survival are almost zero. It is resistant to all known cancer medications and invades nearby tissue rapidly.
About the Author:
Owen Jones, the author of this article, writes on a number of topics, but is now involved with the stages of ovarian cancer. If you would like to know more, please visit our web site at Signs and Symptoms of Ovarian Cancer