Insights into IVF Vs. ICSI

By Serene Anne


The birth of Louise Brown, the world's first "test-tube baby on July 25, 1978 introduced IVF to people around the word. IVF (in vitro fertilization) is a fertility procedure which involves collecting eggs and sperms from a couple and placing them together in a laboratory environment. Usually up to three fertilized eggs (embryos) are transferred into the woman's uterus where implantation and development will occur just as in a normal pregnancy. The average success rate per IVF cycle is approximately 20%.

IVF may be used if the woman is infertile due to a hormonal imbalance, an inability to produce eggs, or damaged or blocked fallopian tubes. An infection or scarring within the uterus and the presence of a tumor may cause her attempts to get pregnant futile. Besides, the older a woman is, the less likely she will be able to conceive children naturally.
However, if a woman is unable to conceive it is not necessarily because she is infertile. According to the National Institutes of Health, USA low sperm count is the cause of 30% - 40% of infertile couple. The general causes of male infertility include reductions in the quality of the sperm and problems with ejaculation. Male infertility is usually diagnosed by a semen analysis.

The man provides a semen sample for a lab to evaluate. The lab will measure the amount of semen and the number of sperm, and to evaluate sperm shape and movement.Intra-cytoplasmic sperm injection (ICSI) was introduced in 1992. It is a fertilization technique that can help a woman who does not get pregnant by in-vitro fertilization.

ICSI can be used to aid males and females had unsuccessful fertilization after standard IVF procedures or could not be accepted for IVF method since there are very little sperm cells or severe sperm abnormalities are present. ICSI helps males and females who do not wish to use donor sperm, as it gives them a greater opportunity of success using the man's own sperm.

ICSI procedure can be used even if the man has had a vasectomy, or has problems with his reproductive organs such as testicles, prostate gland, or seminal vesicles. Indeed, ICSI is beneficial for men with very few sperm counts. At times it is possible to obtain a few sperms from a man who has none recorded during semen analysis by making a testicular biopsy under anesthetic.

A single sperm cell is injected directly into an egg in the laboratory with the help of a microscope and special instruments. Therefore, the sperm do not have to travel to the egg or penetrate the outer layers of the egg. This means that it can help men whos
ICSI can be used to aid males and females had unsuccessful fertilization after standard IVF procedures or could not be accepted for IVF method since there are very little sperm cells or severe sperm abnormalities are present. ICSI helps males and females who do not wish to use donor sperm, as it gives them a greater opportunity of success using the man's own sperm.

ICSI procedure can be used even if the man has had a vasectomy, or has problems with his reproductive organs such as testicles, prostate gland, or seminal vesicles. Indeed, ICSI is beneficial for men with very few sperm counts. At times it is possible to obtain a few sperms from a man who has none recorded during semen analysis by making a testicular biopsy under anesthetic.

A single sperm cell is injected directly into an egg in the laboratory with the help of a microscope and special instruments. Therefore, the sperm do not have to travel to the egg or penetrate the outer layers of the egg. This means that it can help men whose sperm cannot move properly or where the sperm can get to the egg, but is unable to fertilise it for some reason.

ICSI is actually an advanced IVF technique that increases the successful rate of pregnancy by increasing the number of eggs that are fertilised. Normal fertilization occurs in about 75-85% of eggs injected with sperm. (Advance Fertility Centre)




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